Table 3.

Median MICs for study organisms at baseline and at the end point (resistance)

Organism (n)aMedian MIC (μg/ml) ofb:
CeftazidimeCefmenoximeCiprofloxacin
Pre TXResistantPre TXResistantPre TXResistant
E. aerogenes(8)8.1 (2)>32 (1)1.6 (2)37.5 (2)0.02 (4)4 (1)
E. cloacae(11)8.2 (2)NR1.6 (3)50 (3)0.02 (6)NR
E. coli(14)0.2 (4)NR0.5 (4)NR0.01 (6)NR
H. influenzae(6)0.4 (2)NRNDNR0.01 (4)NR
K. pneumoniae(17)2.0 (3)64 (1)1.0 (3)NR0.1 (11)8 (3)
P. aeruginosa(37)6 (4)>32 (1)12.5 (9)c50 (5)0.5 (24)5 (12)
P. mirabilis(6)0.1 (1)NR3.1 (2)NR0.06 (4)NR
S. aureus(5)8 (1)NRNDNR0.4 (4)NR
S. marcescens(11)0.7 (3)32 (1)0.4 (3)25 (1)0.1 (5)NR
  • a Other organisms (number of isolates):Acinetobacter calcoaceticus (1); Citrobacter freundii (1); Citrobacter sp. (1); Klebsiella oxytoca (3); M. morganii (1); Pseudomonas fluorescens (2), P. vulgaris (2); one was resistant [MIC = 50]); S. pneumoniae (1); Serratia rubrifaciens (1).

  • b Pre TX, baseline value; Resistant, end point value; NR, no resistance; ND, not done. Values in parentheses are numbers of isolates.

  • c Range, 3.1 to 12.5 μg/ml.