TABLE 1.

Survival of persistently neutropenic rabbits with primary pulmonary aspergillosis treated with different doses of CAS or AMB compared to that of untreated control rabbits

Treatment group (n)Survival (days)P valueb
Mean ± SEMMedianRange95% CIa
Control (12)6.92 ± 0.696.04–135.40–8.44
CAS (all doses) (36)10.03 ± 0.3610.06–139.31–10.75<0.001
CAS1 (12)10.42 ± 0.5410.07–139.22–11.61<0.001
CAS3 (12)10.17 ± 0.6110.55–138.82–11.52<0.01
CAS6 (12)9.50 ± 0.709.06–137.96–11.04<0.05
AMB (6)8.83 ± 0.489.07–107.61–10.06>0.05
  • a 95% CI, 95% confidence interval.

  • b P values comparing survival values for the treated group to those for the control group were calculated by using ANOVA with Bonferroni’s correction for multiple comparisons.