TABLE 2.

Characteristics of M. tuberculosis isolates from patients

Strain no.Geographic locationTreatment historyaDrug susceptibilitybPolymorphismc
rpokatG or inhAgyrArpsL
ICC14New Delhi+Rr, Ir, OrD516VN35D, NA at second locusS95T
ICC19New Delhi+Rr, Ir, OrL511L, S531LR463LS95T
ICC23New Delhi+Rr, IrL511L, S531LNA
ICC98New DelhiIr, OrR463L, Inh (C/T)S95T
ICC100New Delhi+Rr, Ir, Or, SrS531LR463LS95TNM
ICC101New Delhi+Rr, OrS531LS95T
ICC102New Delhi+Rr, Ir, OrS531LNMS95T
ICC103New Delhi+Rr, Ir, OrL511L, N518TNMA90A, S95T
ICC104New Delhi+Rr, Ir, OrD516VΔ30C, R463LS95T
ICC105New Delhi+Rr, IrK527NR463L
ICC107New DelhiRr, Or, SrN518T, R528PS95TNM
ICC109New Delhi+IrNM
ICC111New Delhi+Rr, Ir, SrS531WInsertion 185CK121K
ICC114New Delhi+IrR463L
ICC115New Delhi+Rr, IrS531WInsertion 98A, R463L
ICC123New Delhi+Rr, Ir, OrR528PNAS95T
ICC124New Delhi+Rr, IrH526YR463L
ICC125New Delhi+RrL511L, S531L
ICC128New Delhi+Rr, Or, SrH526Y, R528HS95TK121K
ICC129New Delhi+Rr, Ir, SrR528PR463LK121K
ICC147New DelhiRr, Ir, OrS531WΔ109G, R463LS95T
ICC203New Delhi+RrD516V
ICC204New Delhi+Rr, IrL521L, K527NR463L
ICC205New Delhi+Rr, IrD516VNA
ICC206New Delhi+Rr, IrS531WNM
ICC208New DelhiRrD516VR463L
ICC209New DelhiRrD516V
ICC210New Delhi+Rr, OrL511V, N518TS95T
ICC211New Delhi+Ir, OrR463LS95T
ICC212New DelhiRrS531L
ICC213New Delhi+Rr, IrR528H, S531WR463L, Inh (C/T)
ICC214New Delhi+IrR463L
ICC215New Delhi+RrS531L
ICC216New Delhi+Rr, SrS531LK121K
ICC217New Delhi+Rr, Ir, OrS531LR463LS95T
ICC218New Delhi+Rr, Ir, OrS522QR463LS95T
ICC219New Delhi+IrT12P, R463L
ICC220New Delhi+Rr, Ir, Or, SrS531WR463L, Inh (T/A)D94G, S95TNM
ICC221New DelhiRr, OrL521LD94A, S95T
ICC222New DelhiOrS95T
ICC223New DelhiRr, OrH526YS95T
ICC225New Delhi+Rr, OrS531LS95T
ICC237NewDelhiRr, OrD516GS95T
ICC239NewDelhi+Rr, IrD516VR463L
ICC240NewDelhi+Rr, IrD516VR463L
ICC242NewDelhi+Rr, OrL511VS95T
ICC244NewDelhi+Rr, Ir, OrS531LA61T, R463LS95T
ICC246NewDelhi+Ir, OrInsertion 185C,R463LS95T
ICC275New Delhi+Rr,OrH526YS95T
ICC277NewDelhi+Rr, Ir, Or, SrH526YΔ30CD94A, S95TK121K
ICC284New DelhiOrNM
ICC286NewDelhi+Rr,IrD516GNM
ICC287NewDelhi+Rr,IrH526YNM
ICC325NewDelhi+Ir, Or,SrNMNMNM
ICC326NewDelhi+Rr, Ir,SrH526LInsertion 98A, R463LNM
ICC327New Delhi+Rr, Ir,SrS509RR463LK121K
ICC328NewDelhiOrNM
ICC408NewDelhi+Rr, Ir, Or, SrQ510H, S531WR463LS95TK121K
ICC425New Delhi+Rr,IrS531LR463L
F4NewDelhi+Rr, OrH526YD94G,S95T
F5New Delhi+Rr,OrS531LS95T
F7NewDelhi+Rr, OrS531LA90V,S95T
F8New Delhi+Rr, OrS531LA90V, S95T
F9New Delhi+Rr, OrN518TS91P, S95T
N31New Delhi+IrR463L
N33NewDelhi+IrR463L
N34NewDelhi+IrR463L
N35NewDelhi+IrD73N, R463L
N36NewDelhiIrR463L
ICC32Ahmedabad+Rr,IrS531LNA
ICC33Ahmedabad+Rr, Ir, OrS509RR463LS95T
ICC36Ahmedabad+Ir,OrR463LS95T
ICC37Ahmedabad+Rr,IrD516GInsertion 98A,R463L
ICC131Ahmedabad+Rr,IrH526Y,R528PR463L
ICC132AhmedabadOrS95T
ICC133Ahmedabad+Rr,IrH526RΔ30C,R463L
ICC134AhmedabadRr, OrS522QS95T
ICC136Ahmedabad+Rr, IrH526RInsertion 98A,R463L
ICC137AhmedabadOrS95T
ICC138AhmedabadOrS95T
ICC226Ahmedabad+Rr,IrL511L, H526RΔ109G,R463L
ICC233Ahmedabad+Rr, IrD516V, H526YΔ30C, R463L
ICC151ChandigarhOrS95T
ICC154ChandigarhRr,Ir, OrS531LΔ30C,R463LS95T
ICC155Chandigarh+IrΔ30C,R463L
ICC159Chandigarh+Rr,OrH526YS95T
ICC161Chandigarh+Rr,OrS522QS95T
ICC162ChandigarhRr,OrS522QS95T
ICC164ChandigarhOrS95T
ICC165ChandigarhOrS95T
ICC166ChandigarhOrS95T
ICC167Chandigarh+Ir,OrR463LS95T
ICC168Chandigarh+OrS95T
ICC169Chandigarh+Rr,IrN518TR463L
ICC170ChandigarhOrS95T
ICC171Chandigarh+Rr,IrS531LR463L
ICC172Chandigarh+Rr,OrS522QS95T
ICC173ChandigarhRr,SrH526LK121K
ICC174Chandigarh+OrS95T
ICC175ChandigarhRr,OrH526YS95T
ICC247ChandigarhRr,OrD516VS95T
ICC248ChandigarhRr,OrD516VS95T
ICC249ChandigarhOrS95T
ICC251ChandigarhOrNM
ICC254Chandigarh+RrS531L
ICC255ChandigarhRr,OrN518TNM
ICC256Chandigarh+Rr, IrH526YNM
ICC257Chandigarh+Rr,OrQ510H,L511LS95T
ICC262Chandigarh+Rr, Ir, OrD516VR463LS95T
ICC95BangaloreOrS95T
ICC96Bangalore+Rr,OrS531LS95T
ICC399Bangalore+Rr,OrS531WNM
ICC524Bangalore+Rr,IrS531LR463L
ICC525Bangalore+Rr, IrS531LR463L
ICC143ShimlaOrNM
ICC144Shimla+IrR463L
ICC145ShimlaOrNM
A3Agra+Rr,Ir, SrS531LR463LNM
A4Agra+Rr,IrD516VR463L
A9Agra+Rr,IrS531LR463L
A11Agra+Rr,IrD516GT11A,R463L
A12Agra+Rr,IrD516VN35D,R463L
A13Agra+Rr,IrD516V,N518TR463L
A14Agra+Rr,IrD516VR463L
A15Agra+Rr,IrS531LR463L
ICC332Jaipur+Rr,IrH526RInsertion 185C, R463L
ICC337Jaipur+Rr,IrS531LR463LS95T
ICC85Chennai+Rr,Ir, OrH526RNAS95T
  • a History of treatment in the previous 20 months.

  • b Rr, rifampin resistant; Ir, isoniazid resistant; Or, ofloxacin resistant; Sr, streptomycin resistant.

  • c NA, no amplification; NM, no mutation; Inh, mutation in the inhA ribosome binding site; Δ, deletion at the indicated nucleotide position.