Table 1.

Demographic and clinical characteristics of the 12 study patients

PatientAge (yr)Ht (cm)Wt (kg)SexaAPACHE II scorebPrincipal diagnosis(es)Infectious diagnosisIsolated pathogen (MIC [μg/ml])Outcome
15516671.0F30End-stage liver diseaseFUOc NoneDied
248183107.4M27End-stage liver diseasePneumonia P. aeruginosa (4),Enterobacter cloacae (1)Died
34216988.4M25End-stage liver diseaseIntra-abdominal sepsisNoneSurvived
45418289.0M31End-stage heart disease, sepsisPneumoniaNoneDied
53416899.9F23Idiopathic thrombocytopenia purpura, respiratory failurePneumonia Klebsiella pneumoniae (1), Moraxella catarrhalis (0.03)Survived
66317399.3M29Congestive heart failure, cardiogenic shockPneumonia Klebsiella oxytoca(0.125)Survived
75917882.2M24End-stage liver disease, sepsisIntra-abdominal sepsis Escherichia coli (0.03)Died
841178133.8M32Thoracic aortic dissectionPneumoniaNoneSurvived
933173108.0F26End-stage heart diseaseFUONoneSurvived
1070204125.3F29Sepsis, rhabdomyolysisCellulitisGroup B streptococci (0.25)Survived
1173172136.0M28Intra-abdominal sepsisIntra-abdominal sepsisNoneSurvived
125217082.8M29Congestive heart failure, cardiogenic shockPneumonia E. coli (0.06),Haemophilus influenzae (0.016)Survived
  • a F, female; M, male.

  • b APACHE II score, Acute Physiology and Chronic Health Evaluation II score on admission to the intensive care unit.

  • c FUO, fever of unknown origin.