Table 3.

Gene products with sequence similarity to the antibiotic resistance gene cluster in SXTMO10

Coding regionaGene nameLength (aa)Closest similarityAccession no.% Identity/rangeb
1–1044 (−) rum′B RumB R391 (C terminus)862633
1457–2047 orf1 197Transposase,P. putida 475481239/188 of 530
2164–5061 orf2 (tnpA)966Transposase,P. putida 746552329/956
5559–7049 orfA 497Putative transposase,E. coli 1031210199/496
7416–7967 (−) dfr18 184Dihydrofolate reductase type VIII283349537/157
7984–8526 (−) orf3 181No homologyNAc NA
8529–9692 (−) orf4 388No homologyNANA
9710–10435 (−) orf5 294Deoxycytidine triphosphate deaminase, P. aeruginosa 994962544/208
10695–11024 orf′A 110Putative transposase,E. coli (3′ end, aa 388–497)10312101
11058–11939 orf6 294No homologyNANA
12159–13370 floR 404FloR (florfenicol exporter), E. coli 1031210099/404
13401–13703 orf7 101Putative transcriptional regulator (LysR family), P. aeruginosa 1135217751/74
13818–14354 orfA′ 179Putative transposase,E. coli (5′ end, aa 1–135)10312101
14332–15165 (−) strB 278Aminoglycoside phosphotransferase420965100/278
15168–15968 (−) strA 267Aminoglycoside phosphotransferase420964100/267
16032–16844 (−) sulII271Dihydropteroate synthase transposase, P. putida (5′ end)1075456100/271
17315–18674 orf2′(tnpA′)746552324
18399–19118 (−) orfB 240Mutl, V. cholerae 12755451/173
(217–345 of 563)
19308–19540 (−) rumB′ RumB R391 (N terminus)862633
19551–19997 (−) rumA 149RumA R39186263298/149
  • a Genes encoded on the minus strand are indicated with (−).

  • b The number of amino acids in a contiguous stretch from which the identity was calculated is shown. The length of the similar protein is also presented.

  • c NA, not applicable.