TABLE 2.

T. mentagrophytes MICs and ΣFICs for combination therapy

StrainMIC80a (μg/ml)FLCb-CsAFLC-FK506
FLCCsAFK506Combined MICcΣFICdCombined MICcΣFICd
DUMC112.0216214/0.50.54/0.030.28
DUMC160.0316810.5/20.284/0.350.6
  • a MIC at which 80% of the isolates tested are inhibited.

  • b FLC, fluconazole.

  • c Shown as MIC of first drug/MIC of second drug, both in micrograms per milliliter.

  • d ΣFIC values represent the median values from two or more experiments.