TABLE 2

Antibiotic susceptibility profiles of Clostridium difficile NAPCR1 isolates

IsolateSmaI patternMIC (μg/ml)a
TetracyclinesLincosamides (CLI)QuinolonesNitroimidazoles (MET)Ansamycins (RIF)Glycopeptides (VAN)Oxazolidinones (LIN)Phenicols (CHL)
TETTIGCIPLEVMOX
LIBA-31474420.380.064≥256256256NAb≤0.251281164
LIBA-2994447640.5≥256128≥25616≤0.25≥3218≥256
LIBA-5701640.064≥256≥32≥32≥320.19NAb11128
LIBA-5711640.094≥256≥32≥32≥320.5NA21128
LIBA-5767640.125≥256128≥25616≤0.2525616≥256
LIBA-5771640.125≥256128≥25616112828≥256
LIBA-6281640.125≥256≥32≥32≥32≤0.25≥320.758≥256
LIBA-2784448640.1258≥32≥32≥322NA18≥256
LIBA-2954320.25≥256128≥256≥320.512848≥256
LIBA-2991640.5≥256128≥256160.5≥3218≥256
LIBA-2993640.5≥256128≥25616≤0.25≥320.1258≥256
LIBA-3125640.25≥256256256≥32≤0.2512816≥256
LIBA-3137640.1258256256≥32≤0.25≤0.12518>256
LIBA-5434320.19≥256256256≥32≤0.251282664
LIBA-5704320.064≥256≥32≥32≥320.125NA1664
LIBA-5707640.094≥256≥32≥32≥320.75NA26128
LIBA-5751640.25≥256128≥25616≤0.2512818≥256
LIBA-5774960.25≥256128≥256≥320.512848≥256
LIBA-6275640.064≥256≥32≥32≥32≤0.25≥321.56128
LIBA-3129449320.125≥256≥256≥256≥32≤0.2512828≥256
LIBA-5719640.094≥256≥32≥32≥32≤0.25NA46128
LIBA-5750640.5≥256128≥256160.512818≥256
LIBA-5755640.25≥256128≥256160.512828≥256
LIBA-5772640.125≥256128≥256160.512818≥256
LIBA-6276640.064≥256≥32≥32≥32≤0.25≥320.75864
LIBA-57344520.250.064≥256≥32≥32≥32≤0.25NA41264
LIBA-2945487640.094≥256≥32≥32≥320.5>3238128
LIBA-5763640.5≥256≥256≥25616≤0.251280.58≥256
LIBA-57691280.5≥256≥256≥25632≤0.25≥3222≥256
LIBA-57701280.5≥256≥256≥25616≤0.25≥3214≥256
LIBA-2992488640.5≥256128≥256160.5≥3218≥256
LIBA-57614890.50.094≥256128≥25616≤0.2512816128
LIBA-57620.250.125≥256128≥25616≤0.2512816≥256
LIBA-3145558640.25≥256≥256≥256≥32≤0.2512816≥256
LIBA-628510.064≥256≥32≥32≥32≤0.25≥320.75864
LIBA-3144578320.125≥256≥256≥256≥32≤0.2512828≥256
LIBA-3150320.047≥256≥256≥256≥32≤0.2512818128
LIBA-5436320.19≥256≥256≥256≥32≤0.2516212≥256
  • a TET, tetracycline; TIG, tigecycline; CLI, clindamycin; CIP, ciprofloxacin; LEV, levofloxacin; MOX, moxifloxacin; MET, metronidazole; RIF, rifampin; VAN, vancomycin; LIN, linezolid; CHL, chloramphenicol. MIC values that indicate resistance or diminished susceptibility are shown in boldface. MICs were obtained with Etests or macrodilution tests.

  • b NA, not assayed.