TABLE 1.

Sequenced and mapped P. aeruginosa luxCDABE mutant strains exhibiting at least twofold-increased ciprofloxacin susceptibilitya

StrainAlleleORFGene nameDescription
H110115_H4PA0353ilvDDihydroxyacid dehydrogenase
H110274_G10PA0836Probable acetate kinase
H110431_C9PA1803lonLon protease
H110574_D9PA1803lonLon protease
H110624_A2PA1803lonLon protease
H110750_F11PA3082gbtGlycinebetaine transmethylase
H110873_E4PA3294Hypothetical protein
H110969_C12PA3617recADNA recombinase RecA
H111076_E9PA3777xseAExodeoxyribonuclease VII large subunit
H111114_E7PA3965Probable transcriptional regulator
H111251_E8PA4163Hypothetical protein
H111382_F7PA4316sbcBExodeoxyribonuclease I
H111498_C2PA4316sbcBExodeoxyribonuclease I
H111581_B12PA4422Conserved hypothetical protein
H111643_C12PA4466Probable phosphoryl carrier protein
H111722_C1PA4700mrcBPenicillin binding protein 1B
H111873_D6PA4700mrcBPenicillin binding protein 1B
H111975_D3PA4756carBCarbamoylphosphate synthetase large subunit
H112081_D2PA4763recNRecN DNA repair protein
H11216_G1PA4961Hypothetical protein
H112280_B7PA5016aceFDihydrolipoamide acetyltransferase
H112322_C5PA5208Hypothetical protein
H112453_F11PA5279Hypothetical protein
H112516_G12PA5345recGATP-dependent DNA helicase RecG