Regimen^{a} | Change in log_{10} CFU/g from 0 to 72 h for strain^{b}: | ||
---|---|---|---|

W04 | W07 | W151 | |

CRO | −0.72 | 0.08 | −0.52 |

CPT | −2.31 | −0.08 | −0.75 |

AMP | −3.8 | −3.15 | −2.76 |

AMP + CRO | −4.65* | −3.58 | −5.66* |

AMP + CPT | −5.05*^{,§} | −4.16* | −5.34* |

↵a CRO, simulations of 2 g ceftriaxone intravenously every 12 h; CPT, 600 mg ceftaroline intravenously every 8 h; AMP, 2 g ampicillin intravenously every 4 h.

↵b Symbols: *, significantly greater log

_{10}CFU/g reduction than with AMP (*P*≤ 0.05); §, significantly greater log_{10}CFU/g reduction than with AMP + CRO alone (*P*≤ 0.05).