Prevalence of carbapenem resistance and resistance mechanisms among bloodstream isolates of Klebsiella pneumoniae, Enterobacter spp., and Escherichia coli, stratified by study site

Medical centeraNo. of carbapenem-resistant bloodstream isolates/total no. of bloodstream isolatesb (%)No. of carbapenem resistance mechanismsc
K. pneumoniaeEnterobacter spp.E. coliKPC-2KPC-3Mechanism other than KPC
A22/128 (17.2)2/36 (5.6)0/25912102
B24/142 (16.9)0/340/3161311d
C18/201 (9.0)0/481/353 (0.3)7111
D7/110 (6.4)1/30 (3.3)1/175 (0.6)243
E24/220 (10.9)1/46 (2.2)0/55994
F5/77 (6.5)0/221/182 (0.5)122
G5/162 (3.1)1/40 (2.5)0/47124
H5/93 (5.4)1/23 (4.3)0/23515
Total110/1133 (9.7)6/279 (2.2)3/2550 (0.1)47518
  • a Medical centers F to H were located outside New York City. A subset of bacteremia episodes from Medical Centers A and B were included in other analyses (13, 54).

  • b Using only the first bloodstream isolate of each species per patient.

  • c Some isolates from medical centers E and F were not available for genotypic analysis to determine the carbapenem resistance mechanism.

  • d —, not available.