Table 1.

Antimicrobial activities of quinolonesa

OrganismMIC (μg/ml)
STFXDU-6856DU-6857DU-6858LVFXOFLXCPFX
E. coliKL-160.0080.0160.0310.0630.0310.0630.008
Citrobacter freundii IID 9760.0080.0160.0310.0630.0310.031≦0.004
Proteus vulgaris08601≦0.0040.0160.0160.0310.0160.0310.008
Proteus mirabilis081030.0080.0160.0310.0630.0310.0630.013
Klebsiella pneumoniae type 10.0310.0310.0630.1250.0630.1250.031
Enterobacter cloacae03400≦0.0040.0080.0310.0630.0310.0310.016
Serratia marcescens101000.0310.0630.0630.1250.1250.250.063
P. aeruginosaPAO10.1250.250.250.50.510.125
Bacterium anitratum ATCC 196060.0630.1250.250.50.250.51
H. influenzae 033803 9606140.0040.0080.0310.0310.0310.0630.031
S. aureus FDA 209-P0.0080.0160.0630.0630.250.50.25
S. epidermidis565000.0630.0630.250.250.510.5
S. pyogenes G-360.0630.1250.50.52>22
Enterococcus faecalis ATCC 194330.250.25112>22
S. pneumoniaeJ240.0310.0630.50.25121
  • a STFX, sitafloxacin; LVFX, levofloxacin; OFLX, ofloxacin; CPFX, ciprofloxacin.