Table 3.

PAEs and PA-SMEs of ceftriaxonea

StrainPAE (h)PA-SME (h) of ceftriaxone at the following multiples of the MIC:
0.1×0.2×0.3×0.4×0.5×
S. aureus ATCC 292310.9 (0.7–1.0)3.0 (2.7–3.3)4.8 (4.1–5.6)7.2 (6.1–8.5)(>15.9–>16.1)(>15.9–>16.1)
S. pneumoniae ATCC 63062.6 (2.3–2.9)2.9 (2.6–3.3)4.2 (3.7–4.9)6.2 (5.7–6.7)(>14.3–>15)(>14.3–>15)
H. influenzae NTCC 8468−0.8 (−0.6–−1.0)−0.6 (−0.3–−1.0)−0.4 (−0.3–−0.6)−0.3 (−0.3)0.4 (−0.3–−1.0)3.8 (0.6–4.4)
E. coli ATCC 25922−2.1 (−2.0–−2.1)−2.1 (−2.0–−2.1)−1.9 (−1.7–−2.1)−1.6 (−1.2–−2.1)−1.3 (−0.7–−1.6)7.1 (5.3–8.3)
  • a Values are means (ranges).