Table 1.

MICs

StrainMIC (mg/liter)
L-749,345ImipenemCeftriaxone
MSSA
 ATCC 292130.50.0164
 30281.00.01616
 20051.00.038
 10502.00.0316
 10031.00.038
MRSA
 Col 184180.5>256
 101120.0316
 55580.25128
 601040.0664
 200740.0632
Penicillin-sensitive S. pneumoniae
 50180.030.0080.06
 10410.030.0160.03
 63060.030.0080.016
 30210.060.0080.06
 20540.060.030.016
Penicillin-resistant S. pneumoniae
 215120.52
 4093220.54
 102020.52
 104610.252
 2003811
Non-β-lactamase-producing H. influenzae
 NTCC 846810.50.008
 1076110.008
 20500.060.50.008
 50560.50.50.004
 506910.50.004
β-Lactamase-producing H. influenzae
 20450.0610.008
 30290.060.50.004
 50440.060.50.004
 10410.060.50.008
 20120.060.50.004
Ampicillin-resistantE. coli
 ATCC 259220.0160.250.125
 10580.0080.50.06
 30030.0160.250.06
 30040.080.250.06
 30540.1250.50.06
Ampicillin-sensitive E. coli
 20930.0080.130.06
 60230.0080.250.125
 20890.0080.250.06
 20840.0080.130.06
 10040.0080.130.06
K. pneumoniae
 ATCC 296650.00810.06
 10280.0080.250.13
 20290.0160.50.06
 40580.0160.50.06
 40010.0080.50.06
Ceftazidime-sensitive E. cloacae
 10130.1250.564
 50090.01611
 60010.1250.250.5
 50280.0610.13
 40020.518
Ceftazidime-resistant E. cloacae
 30250.50.5>256
 101210.5>256
 40060.50.25>256
Ceftazidime-resistant Enterobacter aerogenes
 EN 200.50.25>256
 EN 220.50.25>256
 B 302520.5128
S. marcescens
 140.0310.5
 400.0384
 470.0621
 60030.0342
 20480.0320.5
Citrobacter freundii
 70140.0080.250.06
 40130.0342
 20160.130.5128
 20010.0310.13
 30050.00812
P. aeruginosa
 ATCC 2785316232
 205716232
 50034132
 20608116
 500781128