TABLE 3

MIC values of selected penicillins, cephalosporins, monobactams, and carbapenems against different bacterial strains with or without cyclic boronate 2 supplementation

TABLE 3
  • aMIC values in normal type indicate resistance and those in boldface susceptibility according to current CLSI/EUCAST breakpoints. Shaded values indicate where the MIC is reduced with 10 mg/liter cyclic boronate 2 but either the MIC lies either outside the susceptible range or there is no agreed breakpoint for the drug/organism combination. AMP, ampicillin; AMP/SUL, ampicillin-sulbactam; PIP, piperacillin; PIP/TAZ, piperacillin-tazobactam; TIM/CLAV, ticarcillin/clavulanate; AZT, aztreonam; FAZ, cefazolin; CRO, ceftriaxone; CAZ, ceftazidime; FEP, cefepime; ERT, ertapenem; IMI, imipenem; MEM, meropenem; DOR, doripenem.