Table 2.

Rifampin concentrations in the various compartments

PatientAmt (μg/ml [%]) of rifampin in:
SerumaTumor tissuePerifocal tissueNormal brain tissueCES
113.342.74 (20.5)0.86 (6.5)0.42 (3.2) NDb
29.853.92 (39.8)2.08 (21.1)0.30 (3.0)ND
312.200.36 (2.9)0.22 (1.8)ND0.39 (3.2)
47.481.60 (21.4)0.90 (12.0)0.20 (2.7)0.49 (6.6)
514.401.20 (8.3)0.48 (3.3)0.56 (3.9)0.23 (1.6)
69.860.33 (3.3)0.15 (1.5)0.18 (1.8)0.24 (2.4)
711.760.20 (1.7)0.03 (0.3)0.18 (1.5)0.34 (2.9)
88.320.58 (7.0)0.24 (2.9)0.16 (1.9)0.20 (2.4)
 Mean ± SD10.90 ± 2.431.37 ± 1.34 (12.6)0.62 ± 0.67 (5.7)0.29 ± 0.15 (2.7)0.32 ± 0.11 (2.9)
  • a The concentration of rifampin in serum is taken as 100%.

  • b ND, not done.