Table 1.

Susceptibilities of bacteria and parameters of theEmax model

Microorganism and strainMIC (μg/ml)AUC50 (μg · h/ml)IEmax [(log CFU/ ml) · h]s
S. aureus0.60171981.8
E. coliI0.0130.82301.5
E. coliII0.087.02950.8
P. aeruginosa0.156.02101.1