Table 1.

Comparison of antibacterial activities (MIC90s) of OPC-20011 and OPC-20026

Clinical isolateNo. of strainsMIC90(μg/ml)Ratioa
OPC-20011OPC-20026
MSSA470.781.562
MRSA336.25254
DMPPC-susceptible S. epidermidis 441.563.132
DMPPC-resistant S. epidermidis 343.136.252
E. faecalis 256.2510016
Non-ABPC-susceptible S. pneumoniae 180.050.12
E. coli 541.566.254
K. pneumoniae 263.1312.54
S. marcescens 276.2512.52
P. mirabilis 411.566.254
P. rettgeri 401.566.254
  • a MIC90 of OPC-20026/MIC90 of OPC-20011.