TABLE 1

MICs and MECs of kanamycin or cefotaxime against Enterococcus faecalis or Pseudomonas aeruginosa, alone or in combination with purified C18:1 NASL

Strain and treatmentMIC (mg/liter)MEC (mg/liter)
Enterococcus faecalis
    Kanamycin4–16+2–4
        +2 mg ml−1 C18:1 NASL22–4
        +4 mg ml−1 C18:1 NASL2–4Not determined
    Cefotaxime0.5–20.5–2
        +2 mg ml−1 C18:1 NASL0.5–10.25–1
        +4 mg ml−1 C18:1 NASL<0.016–1<0.062–1
Pseudomonas aeruginosa
    Kanamycin88
        +2 mg ml−1 C18:1 NASL8–168
        +4 mg ml−1 C18:1 NASL<0.25<0.25
    Cefotaxime0.5–40.5–4
        +2 mg ml−1 C18:1 NASL0.5<0.62
        +4 mg ml−1 C18:1 NASL<0.062<0.062