Table 2.

Distribution of P. aeruginosa strains by susceptibility to ciprofloxacin and imipenem and number of mutations in topoisomerase genes

MIC of ciprofloxacin (μg/ml)No. of strains with:
One mutationaTwo mutationsb
Imis cImir dImisImir
21200
43200
82001
160301
320412
641213
1280010
  • a Strains with a single mutation ingyrA or gyrB.

  • b Strains with one mutation in gyrAand one mutation in parC.

  • c Imis, susceptible to imipenem at MIC range of 0.5 to 4 μg/ml.

  • d Imir, resistant to imipenem at MIC range of 8 to 64 μg/ml.