Table 1.

Mutations in the gyrA and parCgenes of different isolates of H. influenzae

StrainMIC of ciprofloxacin (μg/ml)Amino acid change
GyrAParC
Wild typea Ser-84Asp-88Asp-83Ser-84Glu-88
Isolate 12LeuAlaAsn
Isolate 22LeuAlaAsn
Isolate 332LeuAlaAsnArg
  • a The wild type was a quinolone-susceptible clinical strain isolated from a sputum sample from another patient.