Table 4.

Pharmacokinetic parametric values of moxifloxacin and reference drugs in mice

DrugDose (mg/kg)Tmax(h)Cmax (μg/ml)t1/2 (h)AUC24 (μg · h/ml)
Moxifloxacin250.252.01.82.2
500.253.41.94.3
1000.257.51.59.5
Ofloxacina 500.2511.01.313.7
1000.2522.01.332.9
Sparfloxacinb 500.752.85.015.2
1000.758.65.547.9
  • a Data from reference22.

  • b Data from reference 12.