Table 1.

Comparative in vitro activities of different antibiotic compounds against MSSA in relation to ciprofloxacin susceptibility

Test agentMIC (μg/ml)
Ciprofloxacin-susceptible MSSA (n = 34)Ciprofloxacin-resistant MSSA (n = 16)
RangeMIC50MIC90RangeMIC50MIC90
Ciprofloxacin0.12–10.250.54–641664
Clinafloxacin≤0.06≤0.06≤0.06≤0.06–20.51
Grepafloxacin≤0.06–0.12≤0.060.12≤0.06–321632
Levofloxacin≤0.06–0.250.120.250.12–1628
Moxifloxacin≤0.06≤0.06≤0.06≤0.06–20.51
Ofloxacin0.12–10.250.51–32816
Sparfloxacin≤0.06–0.12≤0.06≤0.06≤0.06–80.54
Trovafloxacin≤0.06≤0.06≤0.06≤0.06–20.51
Gentamicin≤0.06–1280.5640.25–>25664>256
Linezolid1–2220.5–212
Quinupristin-dalfopristin≤0.06–40.50.5≤0.06–20.50.5
Vancomycin0.5–2110.5–212