Table 1.

Susceptibilities of study strains to different compounds and effect of tolC and oprM on the function of MexXY

CompoundMIC (μg/ml) for E. colistrain tested
KAM3KAM3/pTEM4 (mexXY)aN43N43/pTEM4 (mexXY)N43tolC::Tn10N43tolC::Tn10/pTEM4 (mexXY)N43tolC::Tn10/ pTEM4/pPMM2 (mexXY oprM)
Acriflavine2164324432
Ethidium bromide1324644232
Erythromycin132812822128
Norfloxacin0.0160.130.030.1250.030.0160.125
Ofloxacin0.0160.130.0160.060.0160.0080.125
Tetraphenyl phosphoniumNTb NT165121616NT
  • a Genes carried on the plasmids are shown in parentheses.

  • b NT, not tested.