Table 1.

Nucleotide substitutions among theblaTEM genes from Tn1(blaTEM-2), Tn2(blaTEM-1B), and Tn3(blaTEM-1A) and those encoding TEM-3, TEM-20, TEM-21, TEM-22, and TEM-29

PositionaGene
blaTEM-1AblaTEM-1BblaTEM-2blaTEM-3blaTEM-20blaTEM-21blaTEM-22blaTEM-29
Promoter region
  32CCTTDeletedNDbTND
 147TTTADeletedND AND
 162GGGGTND GND
 175AGAAAND AND
Coding region
 226cCTCCCCCC
 317CCAACAAC
 346cAAGGGGGA
 436cCTTTTTTT
 512GGGAGAAG
 604cGTGGGGGT
 660AAAAAGAA
 682cTTCCCCCT
 693GGGGGGGA
 747TTTTCTTT
 912CCCCCCGC
 914GGGAAAAG
 925cGGAAAAAG
  • a Numbering according to Sutcliffe (26).

  • b ND, not determined.

  • c Position at which only silent mutations occur.