Table 1.

In vitro activities of antibiotics against B. melitensis isolates (n = 43) in relation to pH

AntibioticMIC (μg/ml)
Range50%90%
pH 7.0pH 5.0pH 7.0pH 5.0pH 7.0pH 5.0
Erythromycin0.5–25632–>2568>256128>256
Azithromycin<0.125–416–>25612561>256
Streptomycin0.25–88–2561162128
Doxycycline<0.125–8<0.125–8<0.1251<0.1252
Rifampin1–32<0.125–120.2521
Ciprofloxacin<0.125–82–>160.50162>16
Ofloxacin<0.125–44–>161161>16