Table 2.

Summary of MFCs (99.99% killing) forAspergillus species tested in this study

Antimicrobial agentMFC (μg/ml)a
A. fumigatusA. terreusA. flavusA. nigerAll
GM50%90%GM50%90%GM50%90%GM50%90%GM50%90%
Liposomal nystatin21.4323232323232323222.63232243232
Nystatin323232323232323232323232323232
Liposomal AB31323232323232323211.3323227.53232
AB lipid complex3232323232323232329.5323227.23232
AB colloidal dispersion27.432323232323232324.4103222.43232
AB8.3123232323210.48.0326.26329.81632
Itraconazole25.4323214.732325.7163217.4323218.43232
Fluconazoleb2,5602,5602,560 NDcNDNDNDNDNDNDNDND2,5602,5602,560
  • a 50% and 90%, MFCs for 50 and 90% of isolates tested, respectively. In calculating the GM values, an MFC of >16 or >1,280 is assumed to be 32 or 2,560 μg/ml, respectively.

  • b Sixteen isolates were tested against fluconazole.

  • c ND, not done.