Table 2.

Influence of various additives to the growth medium on the MIC of different antibiotics

P. aeruginosastrainAdditivebMIC (μg/ml)a
IPMCHLNORTETCFP
H103None0.5250.13.11
Salicylate8250.11.61
Acetyl salicylate4250.21.61
Benzoate4250.13.11
H103/pUCP19None0.5250.21.61
Salicylate8250.13.12
H103/pMC2::mexTNone2>4001.66.31
Salicylate8>4001.63.12
H729oprD::KmrNone8250.11.61
Salicylate8250.21.61
1008None1500.13.11
Salicylate8500.21.62
1008OIR01nfxCNone4>4003.16.31
Salicylate8>4003.13.11
  • a IPM, imipenem; CHL, chloramphenicol; NOR, norfloxacin; TET, tetracycline; CFP, cefpirome. Results are the mean MICs from four to eight determinations.

  • b All additives were used at a concentration of 16 mM.