Table 2.

MICs of β-lactams for N. farcinica VIC,E. coli JM109 harboring recombinant plasmid pFAR-1, and reference strain E. coli JM109

β-Lactam(s)aβ-Lactam MIC (μg/ml) for:
N. farcinica VICE. coli JM109(pFAR-1)E. coli JM109
Benzylpenicillin512 NDb ND
Benzylpenicillin + CLA8NDND
Benzylpenicillin + TZB128NDND
Benzylpenicillin + SUL256NDND
Amoxicillin642562
Amoxicillin + CLA182
Amoxicillin + TZB642562
Amoxicillin + SUL641282
Ticarcillin2565122
Ticarcillin + CLA8161
Ticarcillin + TZB1285121
Ticarcillin + SUL2562562
Piperacillin512321
Piperacillin + CLA3220.5
Piperacillin + TZB256320.5
Piperacillin + SUL256160.5
Cephalothin12884
Cephalothin + CLA6482
Cephalothin + TZB12842
Cephalothin + SUL12842
Cefoxitin12844
Cefoxitin + CLA6444
Cefoxitin + TZB6444
Cefoxitin + SUL6444
Ceftazidime>5120.250.25
Ceftazidime + CLA>5120.250.25
Ceftazidime + TZB>5120.250.25
Ceftazidime + SUL>5120.250.25
Cefotaxime2560.060.06
Cefotaxime + CLA1280.060.06
Cefotaxime + TZB1280.060.06
Cefotaxime + SUL2560.060.06
Aztreonam>51210.12
Aztreonam + CLA5120.120.06
Aztreonam + TZB51210.06
Aztreonam + SUL5120.50.06
Cefepime1280.120.06
Cefepime + CLA64<0.060.06
Cefepime + TZB128<0.060.06
Cefepime + SUL128<0.060.06
Imipenem10.060.06
Imipenem + CLA10.060.06
Imipenem + TZB10.060.06
Imipenem + SUL10.060.06
Meropenem0.25<0.06<0.06
Meropenem + CLA0.25<0.06<0.06
Meropenem + TZB0.25<0.06<0.06
Meropenem + SUL0.25<0.06<0.06
  • a CLA, clavulanic acid at a fixed concentration of 2 μg/ml; TZB, tazobactam at a fixed concentration of 4 μg/ml; SUL, sulbactam at a fixed concentration of 8 μg/ml.

  • b ND, not determined.