Table 4.

MICs of antimicrobial agents for K. pneumoniaestrains that produce different ESBLs and that express or do not express OmpK36 porin

StrainEnzymeMIC (μg/ml)a
FOXCAZFEPPIRIPMMEM
OmpK36 (+)OmpK36 (−)OmpK36 (+)OmpK36 (−)OmpK36 (+)OmpK36 (−)OmpK36 (+)OmpK36 (−)OmpK36 (+)OmpK36 (−)OmpK36 (+)OmpK36 (−)
C1No ESBL4>256130.1250.50.0940.1251.51.5NDND
C1-T6TEM-68>25632>2564323641.51.5NDND
C1-T12TEM-1212>256>256>2564640.56411NDND
C1-T26TEM-268>256>256>2561.5811611NDND
C1-S2SHV-216>256>256>2566>25646434NDND
C1-S3SHV-34192>256>2560.5160.75321.52NDND
C1-S5SHV-5896>256>25636416422NDND
C1-AC248AmpC64>256641280.251142320.2516
C2-AC248AmpC128>256256>256142160.5640.2516
  • a MICs were determined with E-test strips. OmpK36(+), OmpK36 porin expression; OmpK36(−), OmpK36 porin nonexpression; ND, not determined. Antibiotic abbreviations are as in footnotes a of Tables 2 and 3.