Table 1.

Mean days of survival of mice infected withH. capsulatuma

Drug or treatmentDose (mg/kg)No. of days of survivalNo. alive after 30 days
MeanSEM
ControlNone 9.52.41
GM15027.7b2.58
1025.2b3.17
GM25025.7b3.58
1028.4b2.69
GM35030b0.39
1030b010
  • a Mice were infected intravenously with 1.2 × 107 CFU of H. capsulatum, treated from day 2 through 8, and observed for their rate of survival through day 30. Ten mice were in each treatment group.

  • b P < 0.001 compared with the control group.