Table 4.

Activities of BMS-207147 and itraconazole againstCandida species resistant to fluconazolea

Organism and strain no.MIC (μg/ml) of:
BSM-207147Itraconazole
C. albicans
 6-27331616
 10-21390.061.0
 10-73871616
C. glabrata
 16-57894.02.0
 36-88684.016
 27-12818.016
 2-17974.08.0
 17-65808.016
 41-62510.516
C. krusei
 25-25620.52.0
 2-42270.252.0
  • a Fluconazole resistance is defined, according to NCCLS-recommended criteria (7), as a MIC of ≥64 μg/ml.