Table 1.

Strain characterization

StrainOriginGenotypeMIC (μg/ml) of:
RifampinRifabutinRifapentine
T236United StatesK212
T248FranceC25632256
T249FranceB25632256
T250FranceB25632256
T262SloveniaI51264512
T264PolandJ51264256
T295PolandJ25664256
T296PolandJ25664256
T297PolandJ25664256
T397ItalyS512512256
T398ItalyS12864128
T399ItalyQ25664256
T400ItalyR256128256
T401ItalyB51264512
T402ItalyB12832128
T4GermanyA212
T20GermanyB51264512
T25GermanyB112
T36GermanyL51264512
T46GermanyE1,024128512
T59GermanyM5121281,024
T66GermanyH512128512
T109GermanyD>1,024512512
T112GermanyB25664256
T113GermanyD512512256
T115GermanyN212
T118GermanyG25664256
T124GermanyF512256256
T161GermanyO25632256
T166GermanyH512128512
T211GermanyP212
T212GermanyB25632256
T382GermanyD212
T403GermanyD212
T404GermanyD212
T38GermanyD≤0.008≤0.008≤0.008
T38aaThis studyD512256512
T38bbThis studyD512512512
T23GermanyB≤0.008≤0.008≤0.008
T23aaThis studyB424
T23aacThis studyB>1,024512512
T23bbThis studyB1,024256512
  • a Rifampin concentration of 0.0625 μg/ml used for selection of mutants from Rifs MRSA.

  • b Rifampin concentration of 64 μg/ml used for selection of mutants from Rifs MRSA.

  • c Rifampin concentration of 64 μg/ml used for selection of mutants from T23a.