Table 5.

Antimicrobial susceptibility of S. pneumoniaeby specimen sourcea

Antimicrobial agent% Susceptibleb
Blood/CSFc (n = 370)Respiratory tract (n = 682)Ear (n= 85)Eye (n = 58)
Penicillin77.860.9d 44.7d 65.5d
Amoxicillin89.779.0d 58.8d 82.5
Amoxicillin-clavulanate87.276.3d 55.3d 78.9
Ceftriaxone88.479.9d 60.0d 84.2
Erythromycin85.472.9d 65.9d 79.3
Clindamycin96.593.888.2d 87.9d
SXT92.786.6d 77.4d 93.0
Tetracycline90.881.1d 76.2d 77.2d
  • a Of the 1,276 isolates, 81 were from specimen sources other than blood or cerebrospinal fluid, respiratory tract, ear, or eye and were thus excluded from this analysis.

  • b Susceptible by using the interpretive categories recommended by NCCLS.

  • c In addition to blood and cerebrospinal fluid (CSF), samples from other sterile sites may have been included.

  • d The prevalence of susceptible strains was significantly lower (P < 0.05) than that for the blood or cerebrospinal fluid referent group.