Table 5.

IC50s of inhibitors for TEM-type and IRT-type β-lactamases

Strain (enzyme)IC50 (μM)
ClavulanateTazobactam
CF19 (TEM-1)0.180.05
CF29 (TEM-2)0.090.04
CF579 (TEM-57)NDa ND
CF739 (TEM-73 [IRT-18])3112
CF749 (TEM-74 [IRT-19])9.42.9
CF449 (TEM-44 [IRT-13])103.0
CF65a [TEM-65 [IRT-16])9.03.0
  • a ND, not done.