Table 1.

Distribution of primary resistance of H. pylori to antibiotics in different countries determined by the agar dilution method

CountrynFrequency (%) of resistance to:
MetronidazoleaClarithromycinbAmoxicillinc
France4415.92.30
Germany8518.83.40
Norway9341.910
Sweden20326.12.90
UKd + Ireland6026.650
Overall4852730
  • a Resistance as defined in this study, MIC >8 μg/ml (18).

  • b Resistance as defined in this study, MIC >1 μg/ml. Intermediate strains with clarithromycin MICs of 0.25 to 1 μg/ml (18).

  • c No breakpoint was defined.

  • d UK, United Kingdom.