Table 4.

Antimicrobial susceptibility of S. pneumoniaeisolates by nine regions of the United Statesa

Antimicrobial agent% Susceptibleb
New England (n = 57)Mid-Atlantic (n = 125)South Atlantic (n = 205)East North Central (n = 158)East South Central (n = 32)West North Central (n = 172)West South Central (n = 143)Mountain (n = 198)Pacific (n = 184)United States (n = 1294)
Penicillin68.464.060.772.243.8c 61.056.363.174.5c 64.3
Amoxicillin84.274.480.088.6c 65.6c 73.8c 76.278.890.8c 80.5
Amoxicillin-clavulanate82.173.675.186.1c 62.5c 71.972.375.189.7c 77.7
Ceftriaxone82.573.679.089.9c 68.877.975.577.890.8c 80.7
Erythromycin84.277.675.777.853.1c 73.868.8c 77.384.2c 76.4
Clindamycin96.591.292.296.293.893.693.194.492.993.6
SXT91.292.688.392.477.482.6c 76.9c 87.896.2c 88.1
Tetracycline84.274.485.388.681.386.185.278.382.683.1
  • a These regions are defined by the U.S. Bureau of the Census: New England (Maine, Massachusetts, New Hampshire, Rhode Island, Vermont, Connecticut), Mid-Atlantic (New Jersey, New York, Pennsylvania), South Atlantic (North Carolina, Georgia, Florida, West Virginia, District of Columbia, South Carolina, Maryland, Delaware, Virginia), East North Central (Wisconsin, Illinois, Indiana, Michigan, Ohio), East South Central (Alabama, Kentucky, Mississippi, Tennessee), West North Central (Kansas, Iowa, Minnesota, Nebraska, South Dakota, North Dakota, Missouri), West South Central (Texas, Louisiana, Arkansas, Oklahoma), Mountain (Montana, Nevada, Wyoming, Utah, Idaho, Arizona, Colorado, New Mexico), and Pacific (Washington, Alaska, California, Hawaii, Oregon).

  • b Susceptible by using the interpretive categories recommended by NCCLS.

  • c A significant difference exists (P < 0.05) between the antimicrobial susceptibility for this region and the overall prevalence for the United States.