TABLE 4

In vitro activities of PC945, posaconazole, and voriconazole against 96 clinically isolated A. fumigatus strainsa

Test agentMIC (μg/ml)b
RangeGeometric meanModeMIC50MIC90
PC9450.032–>80.17*0.1250.1251
Voriconazole0.064–40.420.50.51
Posaconazole0.016–20.10.0320.0630.5
  • a All MICs were determined visually.

  • b *, P < 0.05 for PC945 versus the results for posaconazole (one-way ANOVA with Tukey's test).