Table 3.

Susceptibilities of P. aeruginosa strains to various antibioticsa

StrainRelevant genotypeMIC (μg/ml)
ApraGentAmkKanNeoTobraNorOfloxCiproLomErmClarClinTet
PAO1Wild type1624128160.25220.54>32>8>3232
3583PAO1(pUCP20)1648128160.5220.254>32>8>3232
3582PAO1(pAMR-1)16282566414418>32>8>3232
3579PAO1Δ(amrR)3248128320.5240.58>32>8>3232
PAO200PAO1Δ(mexAB-oprM)2<123220.25<0.06<0.06<0.0150.13322>320.5
2547PAO1 mutant25632128>512256164418>32>8>3232
35802547Δ(amrB)16216256164210.52>32>8>3216
25482547 mutant>512128256>512>512644418>32>8>3232
  • a Apra, apramycin; Gent, gentamicin; Amk, amikacin; Kan, kanamycin; Neo, neomycin; Tobra, tobramycin; Nor, norfloxacin; Oflox, ofloxacin; Cipro, ciprofloxacin; Lom, lomefloxacin; Erm, erythromycin; Clar, clarithromycin; Clin, clindamycin; Tet, tetracycline.