Table 2.

Strains of C. neoformans used to estimate mutations to fluconazole resistance

StrainMLEE genotypeaGeographic originSampleSerotypeFluconazole MIC (μg/ml) in:
ref. 6Present study
CDC-B4964ET-1ZaireCSFA2
CDC-MAS92-0248ET-1United StatesBloodA162
CDC-Y195-90ET-1BrazilUnknownA4
CDC-Y289-90ET-1CanadaCSFA1
CDC-MAS92-0316ET-2United StatesBloodA11
CDC-MAS92-0368ET-2United StatesCSFA0.51
CDC-MAS92-0804ET-2United StatesCSFA0.52
CDC-MAS92-0037ET-3United StatesCSFA40.25
CDC-MAS92-0064ET-3United StatesBloodA21
CDC-MAS92-0109ET-3United StatesBloodA20.5
CDC-MAS92-0245ET-3United StatesCSFA41
CDC-Y288-90ET-3CanadaCSFA1
CDC-MAS92-0232ET-8United StatesBloodD20.5
CDC-Y286-90ET-8CanadaCSFD2
CDC-Y290-90ET-9CanadaCSFD2
ATCC34875ET-11DenmarkPigeon nestD1
CDC-MAS92-0088ET-12United StatesBloodD12
CDC-MAS92-0403ET-12United StatesBloodD11
CDC-Y494-91ET-12United StatesCSFD1
CDC-B4496ET-19AustraliaCSFB4
E275UnknownAustraliaEucalyptusB2
  • a ET type designations are the same as those in Table 1 and references 6 and8.