Table 1.

Susceptibility of 249 clinical isolates of seven species or taxa of rapidly growing mycobacteria to linezolid as determined by broth microdilution

Species No. (cumulative %) of isolates inhibited by MIC (μg/ml) of: No. of isolates tested
0.25 ≤0.5 1 2 4 8 16 32 64≥128
M. fortuitumgroupa 0 (0) 0 (0) 4 (5)15 (26) 26 (61) 19 (86) 7 (96) 3 (100)0 (100) 0 74
M. fortuitum third biovariant complex 0 (0) 0 (0) 0 (0) 1 (10) 6 (70)3 (100) 0 0 0 0 10
M. abscessus 0 (0) 2 (2) 0 (2) 1 (3) 6 (9) 14 (23)24 (48) 39 (88) 10 (98) 2 (100) 98
M. chelonae 0 (0) 0 (0) 1 (2) 0 (0) 5 (12)21 (54) 20 (94) 2 (98) 1 (100) 0 (100) 50
M. mucogenicum 0 (0) 2 (20) 4 (60)1 (70) 2 (90) 1 (100) 0 0 0 0 10
M. smegmatis groupb 0 (0)1 (33) 0 (33) 1 (67) 1 (100) 0 0 00 0 3
M. immunogenum 0 (0) 0 (0)0 (0) 0 (0) 0 (0) 0 (0) 2 (50) 2 (100)0 0 4
  • a Includes M. fortuitum, M. peregrinum, and M. fortuitum third biovariant complex.

  • b Includes M. goodii and M. smegmatis sensu stricto.