Table 2.

Susceptibility of 249 isolates of rapidly growing mycobacteria to linezolid as determined by broth microdilution

Organism No. of isolates tested MIC (μg/ml)c% Susceptible or intermediate (MIC ≤16 μg/ml)
Range50% 90% Mode
M. fortuitumgroupa 741–32 4 16 4 96
M. fortuitum third biovariant complex 10 2–88 100
M. abscessus 98 0.5–12832 64 32 48
M. chelonae 50 1–648 16 8 94
M. mucogenicum 100.5–8 4 100
M. smegmatisgroupb 3 0.5–4 4 100
M. immunogenum 4 16–32 32 50
 Range or total 249 0.5–1281–32 4–64 0.5–32 48–100
  • a Includes M. fortuitum, M. peregrinum, and M. fortuitum third biovariant complex.

  • b Includes M. goodii and M. smegmatis sensu stricto.

  • c 50% and 90%, MICs at which 50 and 90% of isolates are inhibited, respectively.