Table 3.

Characterization of fluoroquinolone-resistant E. coli strainsa

StrainTopoisomerase mutationsAcrA overexpressionOSTb
GyrAParCGyrBc
CH1S83L D87NS80IND
CH2S83L D87NS80I E84GWT
CH3S83L D87N A93TS80IND++
CH4S83L D87NS80I A108VND
CH5S83L D87NS80IND++
CH6S83L D87NS80IWT++
CH7S83L D87NS80I A108VND++
CH8S83L D87NS80IND
CH9S83L D87N A93TE84KND++
CH10S83L D87NS80I E84GWT++
CH11S83L D87N A93TS80IND++
CH12S83L D87NE84KND++
CH13S83L D87NS80IND
CH14S83L D87Y A93TS80IND
CH15S83L D87NS80IND++
CH16S83L D87Y A93SS80IND
CH17S83L D87NS80IND++
CH18S83L D87NS80IWT
CH19S83L D87NE84KND++
CH20S83L D87YS80IND++
CH21S83L D87N A93TS80I A108VND++
CH22S83L D87NS80IND
CH23S83L D87NE84KND++
CH24S83L D87NS80IWT++
CH25S83L D87NS80IND+
CH26S83L D87NE84KND++
CH27S83L D87NS80IWT++
CH28S83L D87NS80I E84GND
CH29S83L D87NS80IND++
CH30S83L D87NS80IND++
  • a None of the strains showed overexpression of MarA or SoxS.

  • b OST in hexane:cyclohexane (3:1).

  • c WT, wild-type; ND, not determined.