Table 5.

Restoration of sensitivity to select antibiotics in clinical E. coli strains complemented with wild-typeacrR

StrainMIC (μg/ml)a
TetracyclineChloramphenicolNorfloxacin
CH583253194
CH5(pHRPacrR)2773138
CH10258258250
CH10(pHRPacrR)8110378
CH19NDND51
CH19(pHRPacrR)NDND18
CH27448236
CH27(pHRPacrR)202146
CH2975275117
CH29(pHRPacrR)568021
  • a All susceptibilities were determined using gradient plates. ND, not done, since these strains were already relatively sensitive to tetracycline and chloramphenicol.