Table 2.

Distribution of daptomycin MICs for three different genera of bacteria tested in two different broth media

Daptomycin MIC (μg/ml)No. of strains at each MIC and 2 levels of calciuma
1,094 Staphylococcus sp. strains1,096 Streptococcus sp. strains550 Enterococcus sp. strains
25 mg/liter50 mg/liter25 mg/liter50 mg/liter25 mg/liter50 mg/liter
>161
1614
82111094
423123240
2393122130172
174116155651201
0.5251339597385106
0.255365682351618
0.1257321643016
0.065281142
0.031114011
0.01611113
0.008
 Median MIC1.00.250.50.124.01.0
 Geometric mean MIC0.810.300.380.133.341.12
  • a Cation-adjusted Mueller-Hinton broth with calcium adjusted to 25 or 50 mg/liter was used.