Table 3.

Susceptibilities to β-lactam antibiotics of H. influenzae strains transformed with ftsI DNA fragment

Assigned groupStrainaMIC (μg/ml)
AMP CEC CTX CDR CPD CDN CPN MEM
Rd (ATCC51097) 0.25 1 0.0080.25 0.063 0.008 0.016 0.031
IRd3A/H171 16 0.063 1 0.250.063 0.063 0.125
II Rd3A/KK01116 0.063 1 0.5 0.031 0.063 0.125
IIIRd3A/ME8702 16 0.5 2 2 0.1251 0.25
  • a H. influenzae Rd (ATCC 51097) (the recipient) was transformed with PCR-amplifiedftsI gene DNA fragments from group I, II, and III strains as the donors. Transformants were selected on plates containing 5 or 10 μg of CEC per ml. As an example of the transformant nomenclature, Rd3A/ME870 corresponds to Rd strain containing theftsI gene from strain ME870.