Table 2.

Interlaboratory agreement on broth microdilution antifungal susceptibility for Aspergillusspp.a

Antifungal agent and MIC criterion% Agreement [all isolates (itraconazole-susceptible isolates)]
RPMIRPMI-2%M3M3-2%
Itraconazole
 MIC-090 (92)92 (94)90 (91)85 (85)
 MIC-283 (89)88 (94)84 (92)88 (97)
Posaconazole
 MIC-091 (91)88 (87)94 (94)86 (86)
 MIC-296 (96)95 (96)93 (99)91 (96)
Ravuconazole
 MIC-093 (95)87 (85)94 (95)88 (89)
 MIC-288 (89)90 (89)85 (86)81 (82)
Voriconazole
 MIC-097 (97)98 (99)99 (100)93 (92)
 MIC-288 (96)94 (95)90 (92)96 (96)
  • a Species tested were A. fumigatus ( n = 9 ), A. flavus( n = 3 ), and A. terreus ( n = 3 ); 48-h MICs are shown.