Table 1.

Growth rate and distribution of plasmid-encoded 1406A 16S rRNA containing the sequence at position 1192 encoding either the wild type (1192C) or spectinomycin resistance (1192U)a

16S rRNA sequenceDoubling time (min)% Plasmid-encoded 16S rRNA
30S70SDisomesTrisomes
1406A, 1192C4269565150
1406A, 1192U6047292731
  • a Mutant rRNAs were expressed in E. coli strain DH1. The percent plasmid-encoded 16S rRNA in each fraction is the average of at least two experiments. Data for 1406A, 1192C are from Recht et al. (14).