Table 2.

In vitro susceptibilities of 373 clinical isolates ofC. neoformans to posaconazole, itraconazole, and fluconazole

Antifungal agentMIC (μg/ml)% Susceptible at MIC (μg/ml) of:
Range50%90%0.120.250.51
Posaconazole0.015–10.120.5788698100
Itraconazole0.03–10.250.5115994100
Fluconazole0.25–>12881678 (≤8)a
  • a Percent susceptible to fluconazole at ≤8 μg/ml.