Table 3.

Activity of cathelicidin peptides against P. aeruginosa, S. maltophilia, and A. xylosoxidans isolated from patients with CF

PeptidesP. aeruginosaS. maltophiliaA. xylosoxidans
MIC range (μg/ml)MIC50 (μg/ml)MIC90 (μg/ml)MIC range (μg/ml)MIC range (μg/ml)
LL374–6432642–32>32
CAP181–324162–162–32
CAP18-181–641664NTaNT
CAP18-220.5–324164–321–32
mCRAMP1–6432644–32>32
rCRAMP8–643264NTNT
SMAP290.06–8121–81–32
OV-10.125–16816NTNT
OV-20.03–1624NTNT
OV-31–824NTNT
  • a NT, not tested.