Patient no. | C. albicans isolate^{a} | Mean ± SD zone of inhibition (mm)^{b} | ERG11 allele expressed | Amino acid substitution(s) |
---|---|---|---|---|

7 | 412 (S) | 43.75 ± 1.12 | 412 | K128T |

2307 (R) | 43.08 ± 0.90 | 2307 | K128T | |

14 | 1632 (S) | 42.80 ± 1.93 | 580 | None |

1640 (R) | 44.18 ± 0.75 | 1640 | V437I | |

15 | 945 (S) | 32.50 ± 0.70^{c} | 945 | D116E, G450E |

1619 (R) | 0^{c}
| 1619-1 | D116E, G450E, G307S | |

32.80 ± 1.35^{c} | 1619-2 | D116E, G450E | ||

16 | 3107 (S) | 14.50 ± 1.24^{c} | 3107 | Y132F |

3119 (R) | 15.57 ± 3.94^{c} | 3119 | Y132F | |

28 | 5044 (S) | 36.81 ± 0.91^{c} | 5044 | V437I, D446N |

5052 (R) | 37.56 ± 2.00^{c} | 5052 | V437I, D446N | |

30 | 5106 (S) | 43.37 ± 1.50 | 5106 | V437I |

5108 (R) | 30.58 ± 0.79^{c} | 5108 | V437I, G464S | |

42 | 1691 (S) | 42.87 ± 0.83 | 1691 | K128T |

3731 (R) | 0^{c}
| 3731-1 | F126L, K143R | |

22.33 ± 0.52^{c} | 3731-2 | K143R | ||

51 | 2274 (S) | 31.55 ± 1.85^{c} | 2274 | S405F |

2257 (R) | 33.16 ± 1.83^{c} | 2257 | S405F | |

2339 (R) | 33.07 ± 1.64^{c}
| 2339 | S405F | |

59 | 3917 (S) | 42.62 ± 1.50 | 3917-1 | None |

32.62 ± 1.19^{c}
| 3917-2 | F449S | ||

4617 (R) | 21.05 ± 0.87^{c} | 4617 | F449S, T229A | |

4639 (R) | 24.37 ± 1.60^{c} | 4639 | F449S, T229A |

↵a S, susceptible; R, resistant.

↵b Mean diameters were obtained by measuring the zones of inhibition produced by 10 independent

*S. cerevisiae*Leu^{+}transformants. The mean diameter for YKKB-13 transformed with YEp51 alone was 63 mm. The mean diameter for YKKB-13 transformed with a susceptible control was 43 mm. The mean diameter for YKKB-13 transformed with a resistant control was 0 mm.↵c P < 0.05 .